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Answer: ONEANDDONE
ONEANDDONE is a crossword puzzle answer that we have spotted 6 times.
Single-use
Like a team that loses in the first round
Apt. idiom for an only chid's parents
Never to be repeated ... or an apt pronouncement after following the instructions sequentially in 17-, 25-, 39- and 49-Across?
Not to be repeated
Like some NBA prospects, or like the answers to the starred clues