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Answer: TOBACCO
TOBACCO is a crossword puzzle answer that we have spotted 19 times.
Powerful Washington lobby
Popular vice
Snuff stuff
Nightshade family member
Pipe filler
Jamestown crop
Slow-burning leaf
Crop with a powerful Washington lobby
Shag, e.g.
It goes up in smoke
Virginia crop
Pipe fill
Cash crop for the southern American colonies
Caldwell's "___ Road"
Cigarette filling
Leaves for a cigar
Important Colonial cash crop
Something used in a pinch?
Major crop of North Carolina