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Answer: TAINT
TAINT is a crossword puzzle answer that we have spotted 49 times.
"___ so!"
Sully
Slight contamination
Discredit
Corrupt
Despoil
Tarnish
Rejoinder to "'Tis!"
"___ funny, McGee!"
Infect
Trace of dishonor
Slangy denial
Poison
Old-fashioned contraction
Besmirch
Opposite of purify
Cast aspersions on
Adulterate
Dogpatch negative
Spoil
Stigmatize
Contaminate
Slangy opposite of 'tis
Make impure
Mark of Cain
''___ funny, McGee!''
'Tis counter
Ruin morally
Tarnish, as a reputation
Render impure
Opposite of "'tis"
"'Tis!" response
Disgrace trace
Blemish
Perineum, slangily
Pollute
Befoul
Stain
Dirty
Contaminate, as water
Make dirty
Hint of scandal
Go bad, as meat
Corrupt, as evidence
Opposite of "purify"
Vitiate
"but never ___ my love": Shak.
Apt letters missing from con_ _m_ _a_e
Contaminating trace