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Answer: SPAYED
SPAYED is a crossword puzzle answer that we have spotted 15 times.
Neutered
Incapable of littering
Like many a pet
Did a vet's job
Did a vet's job
Neutered, as a pet
Fixed, as a dog
Fixed, in a way
Having the ovaries removed
Kept from littering
Incapable of littering?
Homophone for spade
Prevented from littering
Fixed
Fixed by a 21-Across