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Answer: SETOFF
SETOFF is a crossword puzzle answer that we have spotted 22 times.
Counterbalance
Trigger
Leave home
Detonate
Depart
Ignited
Begin a journey
Ignite
Cause, as an explosion
Spur, as a chain reaction
Fire, as a firecracker
Start out
Hit the road
Leave port
Start a journey
Trip
Trip ... or start a trip
Ignite, as a cherry bomb
Ignite, as an explosion
Trigger, as an alarm
Cause
Trip, as an alarm