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Answer: SADNESS
SADNESS is a crossword puzzle answer that we have spotted 21 times.
Gloom
The blues
Melancholy
Funk
Cause of crying
Sorrow
Blue state
Unhappy state
Despair
Low spirits
Dysphoria
Cause to suffer
Depression
Blue quality
Gloomy state
Opposite of euphoria
Blue state?
Woe
Grief
Blue character in Pixar's "Inside Out"
Melancholy feeling