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Answer: RILES
RILES is a crossword puzzle answer that we have spotted 54 times.
Bugs
Gets to
Angers
Tees off
Stirs up
Burns up
Vexes
Ticks off
Ruffles
Pesters
Makes mad
Agitates
Gets one's goat
Gets in a lather
Steams up
Nettles
Provokes
Whips into a frenzy, with "up"
Makes angry
Aggravates
Infuriates
Engages in rabble-rousing
Bugs to no end
Needles or nettles
Gets one's dander up
Irritates
Works up
Angers, with "up"
Ruffles feathers
Annoys
Stirs (up)
Incenses
Peeves
Gets upset
Irks
Works (up)
Exasperates
Infuriates, with "up"
Inflames
Antagonizes
Gets all stirred up
Gets one's dudgeon up
Rubs the wrong way
Grates on
Makes furious
Bugs a lot
Incites to pique
Makes angry, with "up"
Invokes the anger of
Makes hopping mad
Gets one's 53-Down
Makes incensed
Stirs to anger
Really gets to