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Answer: POLIO
POLIO is a crossword puzzle answer that we have spotted 47 times.
Salk's conquest
Salk's target
Old disease
F.D.R. affliction
Bygone epidemic cause
Vaccine target
FDR's affliction
Salk vaccine target
Dr. Sabin studied it
Sabin vaccine target
Dr. Salk's conquest
Largely eradicated disease
Sabin's study
Jonas Salk's target
Jonas Salk's concern
F.D.R.'s affliction
FDR affliction
F.D.R.'s affliction
What Dr. Salk helped cure
Target of Salk's vaccine
Disease almost eliminated
Target of the Salk vaccine
Salk vaccine's target
Salk foe
Jonas E. Salk's target
Salk's study
March of Dimes' original crusade
Infantile paralysis
See 6-Across
Challenge for F.D.R.
FDR's inhibitor
Crippling disease
Subject of the 1954 Nobel Prize in Medicine
Jonas Salk's study
Affliction suffered by FDR
Focus of University of Pittsburgh research, 1948-1955
Salk's focus
Salk conquered it
Salk cured it
Jonas Salk's conquest
Sabin developed a vaccine for it
Study for Dr. Albert Sabin
Roosevelt's affliction
Albert Sabin developed a vaccine for it
Disease largely eradicated by Salk's vaccine
Health problem now largely eradicated in the U.S.
Oral vaccine target