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Answer: OPPOSITE
OPPOSITE is a crossword puzzle answer that we have spotted 15 times.
Facing
Like the prepositions in 23-, 35- and 46-Across
Antithesis
Antithetical
Black, to white
Night, to day
Antonym
On the other side
Directly across from
For, for against
Reverse
Polar
Left, to right
Top, to bottom
Inverse