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Answer: NERVOUS
NERVOUS is a crossword puzzle answer that we have spotted 11 times.
With 19-Across, a worrywart
On edge
___ Nelly
Edgy
Acutely uncertain
Like one afflicted with the added elements in 17-, 24-, 53- and 65-Across?
Tense
Full of butterflies
Anxious
Feeling edgy
How you might feel before a first date