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Answer: LOSEIT
LOSEIT is a crossword puzzle answer that we have spotted 30 times.
Flip out
Flip
Go ballistic
Snap
Come unglued
Freak out
Go nuts
Go postal
Fly into a rage
Freak
Have a tantrum
Go bananas
Blow one's top
Go bonkers
Blow up, maybe
*Face
Go berserk
Go completely nuts
Blow up
Blow one's lid
Go ballistic
Blow one's top
Go to pieces
Become unglued
Go ape
Blow a fuse
Finally crack
Fly off the handle
Go completely bananas
Succumb to one's emotions