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Answer: ISUS
ISUS is a crossword puzzle answer that we have spotted 6 times.
"We have met the enemy and he ___"
"We have met the enemy and he ___!" (Pogo)
"We have met the enemy and he ___": Pogo
"We have met the enemy and he ___" (Pogo)
'We have met the enemy ... and he ___': Pogo
See 63-Across