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Answer: ISS
ISS is a crossword puzzle answer that we have spotted 51 times.
Magazine: Abbr.
Mag. edition
Magazine no.
No. of People, say
Periodical output: Abbr.
Magazine output: Abbr.
Mag. copy
Life week (abbr.)
Newspaper unit (abbr.)
Unit of Time: Abbr.
Edition: Abbr.
Mag. stand item
One may come out each mo.
One of Us?: Abbr.
Mag. unit
Newsstand item: Abbr.
Newsstand no.
NASA destination
Shuttle destination
Shuttle's destination
NASA outpost
NASA orbiter
NASA orbitor
Particular mag. printing
Particular printing: Abbr.
Particular magazine printing: Abbr.
Magazine printing Abbr.:
Magazine edition: Abbr.
DC Comics collectible: Abbr.
Mir successor
Particular mag. edition
Orbiting loc.
Soyuz destination
Limited edition?
There's one every year for Person of the Year: Abbr.
One New Yorker, e.g.: Abbr.
Specific mag. printing
Vol. 1, No. 1, e.g.
Orbiting lab, for short
Orbiting research facility: Abbr.
Magazine unit: Abbr.
NASA's six-person orbiter
Mag. printing
Long-term astronaut's home: Abbr.
Satellite inhabited continuously since 2000: Abbr.
Mag. number
Long-term digs in orbit: Abbr.
Research outpost co-developed by NASA
39-Across successor: Abbr.
Site used by NASA, in brief
Astronauts' outpost, for short