Answer: IRENE
IRENE is a crossword puzzle answer that we have spotted 390 times.
    - Adler of Sherlock Holmes stories
 
    - "Goodnight" girl of song
 
    - 1973 Broadway revival starring Debbie Reynolds
 
    - Hit 1919 musical revived in 1973
 
    - Wife of two Forsytes, in "The Forsyte Saga"
 
    - Goddess of peace
 
    - One of the Horae
 
    - Singer Cara
 
    - Personification of peace, in myth
 
    - Dunne of "I Remember Mama"
 
    - With 23-Down, "Zorba the Greek" actress
 
    - Sherlock's lady friend
 
    - "The Woman," to Sherlock
 
    - Castle of old
 
    - Papas in films
 
    - With 68-Down, "Fame" actress
 
    - Cara of "Fame"
 
    - Rich or Worth
 
    - Actress Worth
 
    - Goodnight girl of song
 
    - Holmes friend Adler
 
    - ___ Castle
 
    - Actress Pappas
 
    - Tony-winner Worth
 
    - Memorable 1999 hurricane
 
    - 1999 hurricane
 
    - Actress Papas
 
    - Peace goddess
 
    - Abstract artist __ Rice Pereira
 
    - Woman in Sherlock Holmes stories
 
    - Cara or Castle
 
    - Castle in a ballroom
 
    - Papas on the screen
 
    - Castle of dance
 
    - "Goodnight ___"
 
    - "Goodnight ___" (1950 hit)
 
    - Papas of "Zorba the Greek"
 
    - Vernon and __ Castle, introducers of the turkey trot
 
    - "Prizzi's Honor" heroine
 
    - "Me, Myself & ___" (2000 flick)
 
    - "Good Night" girl of song
 
    - Destructive 1999 Florida hurricane
 
    - In an old song, the "I'll see you in my dreams" girl
 
    - Nine-time Obie-winning playwright Maria ___ Fornes
 
    - Mrs. David O. Selznick, daughter of 1-Across
 
    - Castle with many steps
 
    - Ryan of "The Beverly Hillbillies"
 
    - 2000 Renée Zellweger title role
 
    - Daughter of Zeus
 
    - Castle in a dance hall
 
    - Sister of Queen Beatrix of the Netherlands
 
    - 1919 Broadway musical that set a record for most performances up to that time
 
    - "Me, Myself & ___," 2000 Jim Carrey film
 
    - Godfrey's woman in "My Man Godfrey"
 
    - One of the Forsytes in "The Forsyte Saga"
 
    - Jim Carrey comedy "Me, Myself & ___"
 
    - Ballroom dancer Castle
 
    - Younger sister of the Netherlands' Queen Beatrix
 
    - Emmy and Tony nominee Ryan
 
    - ___ Adler of Conan Doyle's "A Scandal in Bohemia"
 
    - Comedic title role for Renée Zellweger, 2000
 
    - Actress Papas or Ryan
 
    - Girl who's the "you" in the lyric "I'll see you in my dreams"
 
    - Ryan of "Pippin"
 
    - Adler who outwitted Sherlock Holmes
 
    - Title woman in a Jim Carrey movie
 
    - Classic Broadway musical with the song "Alice Blue Gown"
 
    - 1973 musical for which George S. Irving won a Tony for Best Actor
 
    - Actress Ryan of "The Beverly Hillbillies"
 
    - Cantankerous "Granny" Ryan
 
    - Actress Dunne of "Penny Serenade"
 
    - Castle of the ballroom
 
    - Actress Dunne
 
    - "Me, Myself & ___"
 
    - Vernon Castle's dance partner
 
    - Castle or Cara
 
    - Goodnight gal of song
 
    - Dunne or Papas
 
    - "Me, Myself & ___" (Jim Carrey flick)
 
    - Goodnight girl
 
    - Castle of dancing
 
    - Greek goddess of peace
 
    - She played Granny in "The Beverly Hillbillies"
 
    - Castle with many steps?
 
    - "Goodnight ___" (song written by 34-Across)
 
    - Peace personified
 
    - "Goodnight ___" (Leadbelly song)
 
    - Cara of “Fame”
 
    - Castle or Dunne
 
    - Castle with a lot of steps?
 
    - "Me, Myself & ___" (Carrey comedy)
 
    - Cara of "Fame" fame
 
    - Jim Carrey movie "Me, Myself and ___"
 
    - Actress Ryan on "The Beverly Hillbillies"
 
    - Tony-winning actress Worth
 
    - Dancer Castle
 
    - Woman of the good night?
 
    - Cara of song
 
    - Dunne of "Cimarron"
 
    - Papas of "Z"
 
    - Peaceful personality of myth
 
    - Worth or Castle
 
    - Papas of "Anne of the Thousand Days"
 
    - Castle of ballroom dancing
 
    - Adler admired by Sherlock Holmes
 
    - Castle with lots of steps?
 
    - "Fame" singer Cara
 
    - Castle led by another
 
    - "I'll see you in my dreams" girl of song
 
    - 1935 Nobelist Joliot-Curie
 
    - Actress Cara
 
    - Three-time Tony winner Worth
 
    - Personification of peace, in mythology
 
    - "Goodnight, ___" (folk standard)
 
    - Greek counterpart of Pax
 
    - "A Streetcar Named Desire" producer ___ Mayer Selznick
 
    - "Brave ___" (William Steig children's book)
 
    - "Me, Myself & ___" (2000 comedy)
 
    - With 2-Down, "Fame" singer
 
    - "Pippin" actress Ryan
 
    - Old-time actress Dunne
 
    - Castle with steps
 
    - "I'll see you in my dreams" song girl
 
    - Mythological peace goddess
 
    - Dancing Castle
 
    - Dunne in Hollywood
 
    - ''Fame'' singer Cara
 
    - Broadway title role for Debbie Reynolds
 
    - Cara of ''Fame''
 
    - Mrs. Soames Forsyte
 
    - Personification of peace
 
    - Renée role of 2000
 
    - Dovish deity
 
    - ''Me, Myself & __'' (Carrey film)
 
    - ''Me, Myself & ___'' (Jim Carrey vehicle)
 
    - Woman in some Sherlock Holmes stories
 
    - Lead Belly classic ''Goodnight, ___''
 
    - Cara in "Fame"
 
    - "Granny" Ryan
 
    - Ryan or Cara
 
    - Sherlock's infatuation
 
    - Ryan of "Beverly Hillbillies"
 
    - Castle of the turkey trot
 
    - ''Goodnight'' girl of song
 
    - Ryan of ''The Beverly Hillbillies''
 
    - Famous Castle
 
    - Dunne of ''I Remember Mama''
 
    - Pierre and Marie's daughter
 
    - Cara or Ryan
 
    - ''Goodnight, ___'' (1950 hit)
 
    - ''Me, Myself & ___'' (Carrey film)
 
    - Role for Zellweger
 
    - ''Goodnight'' lady
 
    - ''Goodnight'' gal
 
    - "Flashdance" singer Cara
 
    - Vernon's dancing partner
 
    - Woman admired by Sherlock
 
    - Ryan who played a hillbilly
 
    - The personification of peace
 
    - "Goodnight, ___" (1950 hit)
 
    - "Me, Myself and ___"
 
    - Galsworthy heroine
 
    - Renee, opposite Jim Carrey
 
    - Galsworthy's Mrs. Forsyte
 
    - Chemistry Nobelist Joliot-Curie
 
    - "Me, Myself & ___," 2000 Jim Carrey movie
 
    - Dunne who was a five-time Best Actress nominee
 
    - Sherlock Holmes' friend Adler
 
    - Good-night girl of song
 
    - "Me, Myself & ___" (Jim Carrey movie)
 
    - "Goodnight" girl of old song
 
    - Curie Daughter
 
    - Adler of the Sherlock stories
 
    - "Me, Myself & __": 2000 film
 
    - Castle the dancer
 
    - Cara on the "Flashdance" soundtrack
 
    - Rich of old films
 
    - Cara or Dunne
 
    - Goddess who carried a cornucopia
 
    - Cara of "Flashdance"
 
    - Broadway musical of 1919 and 1973
 
    - To whom "I'll see you in my dreams" is sung
 
    - "Me, Myself  ___" (Carrey film)
 
    - "Goodnight" lady
 
    - "Me, Myself & ___" (Jim Carrey vehicle)
 
    - Lead Belly classic "Goodnight, ___"
 
    - "Me, Myself & ___": 2000 film
 
    - Actress Papas or Dunne
 
    - "Goodnight" girl
 
    - Dunne with five Oscar nominations
 
    - Old Hollywood's Dunne
 
    - Mythical peace goddess
 
    - Dunne in "Cimarron"
 
    - "Me, Myself & ___" (Carrey film)
 
    - Cara of Fame
 
    - Samuel Johnson tragedy
 
    - Dunne or Cara
 
    - Dunne of "My Favorite Wife"
 
    - Ryan who played Granny on "The Beverly Hillbillies"
 
    - Byzantine empress
 
    - Archie Bunker's liberal neighbor Lorenzo
 
    - "Me, Myself & ___" (2000 film)
 
    - 2000 comedy "Me, Myself & ___"
 
    - Title role for Renee Zellweger
 
    - Hurricane of 2011
 
    - Dutch princess who's the daughter of Queen Juliana
 
    - Vernon Castle's wife
 
    - Mrs. Forsyte in "The Forsyte Saga"
 
    - "Goodnight, ___" (#1 hit of 1950)
 
    - Marie Curie's daughter
 
    - Papas of 'Z'
 
    - Castle that danced
 
    - 'Goodnight' girl
 
    - First name of 8-Down
 
    - Vernon Castle's partner
 
    - 'Me, Myself, and ___'
 
    - 'Goodnight'  girl
 
    - 'Z' actress Papas
 
    - 'Fame' star Cara
 
    - 'Goodnight' girl of song
 
    - With 60-Across, she played Granny on 'The Beverly Hillbillies'
 
    - Actress Ryan
 
    - 'Fame' singer Cara
 
    - Worth of the theater
 
    - Daughter of Zeus and Themis
 
    - Memorable 2011 hurricane
 
    - Holmes adversary Adler
 
    - Ryan or Dunne
 
    - Dunne of films
 
    - Major 2011 hurricane
 
    - She bests Sherlock in "A Scandal in Bohemia"
 
    - Castle seen in "The Whirl of Life"
 
    - "Fame" actress Cara
 
    - 2011 Category 1 hurricane
 
    - Woman's name meaning "peace"
 
    - 'Good-night' girl
 
    - She pounded the East Coast in 2011
 
    - Cary's costar in "The Awful Truth"
 
    - Name meaning "peace"
 
    - Goodnight gal
 
    - "Goodnight, ___" (1950 The Weavers hit)
 
    - Cary's co-star in "The Awful Truth"
 
    - Sherlock's adversary Adler
 
    - "Fame" star Cara
 
    - 2011 hurricane
 
    - Screen legend Dunne
 
    - Rachel's role in the 2009 Sherlock Holmes movie
 
    - Castle on Broadway
 
    - Worth of theater
 
    - Ryan who played Granny
 
    - Samuel Johnson's only play
 
    - She outwitted Sherlock
 
    - The "you" in the lyric "I'll see you in my dreams"
 
    - Girl to whom "goodnight" is sung
 
    - Adler introduced in "A Scandal in Bohemia"
 
    - Damaging 2011 East Coast hurricane
 
    - Outwitter of Sherlock
 
    - Peaceful deity
 
    - Jim Carrey film, "Me, Myself & ___"
 
    - 2000 title role for Renée
 
    - Worth or Dunne
 
    - 2011 hurricane that hit New York City
 
    - Goodnight ______
 
    - Dunne, Cara, or Ryan
 
    - East Coast storm of 2011
 
    - Memorable hurricane of 2011
 
    - Nobel winner Joliot-Curie
 
    - 2011 East Coast hurricane
 
    - Big hurricane of 2011
 
    - Worth or Rich
 
    - Peace in Greece
 
    - Ryan who was Granny
 
    - Castle of fame
 
    - Pax's Greek counterpart
 
    - Follower of a destructive path in 2011
 
    - "Forsyte Saga" wife
 
    - Woman "in my dreams," in song
 
    - Daughter of Queen Juliana of the Netherlands
 
    - Dunne of film
 
    - Dunn of "Magnificant Obsession"
 
    - With 11-Down, "Zorba the Greek" actress
 
    - Destructive hurricane of 2011
 
    - Tony winner Worth
 
    - "Me, Myself & ___": Jim Carrey film
 
    - Woman in some Sherlock stories
 
    - Good night ______
 
    - Ryan of old TV
 
    - Adler of Sherlock Holmes lore
 
    - Actress Rich
 
    - Destructive 2011 East Coast hurricane
 
    - "Goodnight" girl of an old song
 
    - "Good Night" girl
 
    - Sherlock's feminine adversary
 
    - Longest-running Broadway musical until "Pins and Needles" in 1939
 
    - Castle in the 1914 musical "Watch Your Step"
 
    - Me Myself and ____, 2000 movie with 34 Down
 
    - Cara of 'Fame'
 
    - "The woman," to Sherlock Holmes
 
    - Rachel, in "Sherlock Holmes"
 
    - Marie Curie's Nobelist daughter
 
    - Dunne of movies
 
    - Rachel, in recent "Sherlock Holmes" films
 
    - "Me, Myself and ___" (Carrey movie)
 
    - Madame Curie daughter
 
    - Actress Jacob
 
    - Rachel, in two recent "Sherlock Holmes" films
 
    - Sherlock Holmes' Ms. Adler
 
    - Nobel Prize-winning daughter of the Curies
 
    - Sherlock's female adversary
 
    - "Me, Myself & ___" (Jim Carrey film)
 
    - Worth of the stage
 
    - Dunne of old Hollywood
 
    - Worth of acting
 
    - Cara famous for "Fame"
 
    - Mythical goddess of peace
 
    - ___ Neuwirth (designer jewelry brand)
 
    - "Me, Myself & ___" (film)
 
    - Cara or Papas
 
    - Sherlock Holmes' Adler
 
    - A sister of Eunomia
 
    - The "she" in the line "To Sherlock Holmes she is always THE woman"
 
    - "Me, Myself & ___" (movie)
 
    - Goddess of peace (var.)
 
    - Singer-actress Cara
 
    - Castle with famous steps
 
    - "Me, Myself & ___" (Carrey movie)
 
    - Cara who sang "Flashdance ... What a Feeling"
 
    - Greek peace goddess
 
    - Pax, to Praxiteles
 
    - Good night ___ ( Sing-along favourite )
 
    - Cara with two Grammys
 
    - A castle
 
    - Papas from Greece
 
    - 2011 Atlantic hurricane
 
    - Papas or Bordoni
 
    - Adler in "A Scandal in Bohemia"
 
    - Goodnight woman of song
 
    - Adler in Sherlock Holmes stories
 
    - Daughter of the law and order Titaness
 
    - "Flashdance...What a Feeling" singer Cara
 
    - "Me, Myself & ___" (Jim Carrey comedy)
 
    - Woman who's bid good night in an old song
 
    - Lead Belly's "Goodnight ___"
 
    - Adler of Holmes stories
 
    - Sherlock's foe Adler
 
    - Bedard who voiced Pocahontas
 
    - It followed Tropical Storm Harvey in 2011
 
    - Five-time Oscar nominee Dunne
 
    - Actress Bedard
 
    - Protector of ancient Athens
 
    - Adler of Sherlock Holmes fame
 
    - "Goodnight, ___" (Lead Belly song)
 
    - 4th Impact singer Cercado
 
    - Adler in Sherlock Holmes fiction
 
    - Sherlock Holmes foil Adler
 
    - ___ Neuwirth (jeweler)
 
    - Bedard who voiced Pocahontas in the 1995 Disney film
 
    - Name from the Greek for "peace"
 
    - "Goodnight, ___" (classic song)
 
    - Nobel-winning daughter of Marie and Pierre Curie
 
    - Dunne or castle
 
    - Red Velvet singer
 
    - Nobelist Joliot-Curie
 
    - Adler called "the woman" by Sherlock Holmes
 
    - Joliot-Curie who won a Nobel Prize in chemistry
 
    - Adler in the Sherlock Holmes canon
 
    - "Lost in Yonkers" Tony winner Worth
 
    - "Goodnight, ___": Lead Belly song
 
    - "Fame" singer-actress Cara
 
    - Nobel-winning chemist Joliot-Curie
 
    - Dunne of classic screwball comedies
 
    - Name hidden in "the fire next time"
 
    - Oscar nominee Dunne
 
    - Cara who sang "flashdance... what a feeling"
 
    - Cara of fame
 
    - Fame actress Cara
 
    - One-named K-pop singer
 
    - Name that becomes another name when its first letter is dropped
 
    - Adler played by Lara Pulver on "Sherlock"
 
    - ___ Joliot-Curie, chemist daughter of Marie
 
    - Subject of the classic song lyric "I'll see you in my dreams"
 
    - Nobel laureate Joliot-Curie
 
    - "Flashdance ... What a Feeling" singer Cara
 
    - Name derived from the Greek for "peace"
 
    - Dunne of "Love Affair"
 
    - Sherlock adversary Adler
 
    - Leader of the girl group Red Velvet
 
    - Greek goddess who is the equivalent of the Roman Pax
 
    - She outwitted Sherlock in "A Scandal in Bohemia"
 
    - Red Velvet leader