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Answer: GOMAD
GOMAD is a crossword puzzle answer that we have spotted 19 times.
Lose it
Lose one's mind
Flip out
Lose one's marbles
Lose your marbles
Snap
"If I don't write to empty my mind, I __": Byron
Flip one's lid
Descend into dementia
Flip
Come unglued
"If I don't write to empty my mind, I ___": Byron
Crack up
Lose touch with reality
Freak
Hit the ceiling
Wig out
Lose one's grip
Do as Henry VI did