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Answer: GALL
GALL is a crossword puzzle answer that we have spotted 50 times.
Effrontery
More than irk
Chutzpah
Brass
Crust
Rub the wrong way
Annoy no end
Nerve
Boldness to a fault
It may be unmitigated
Impudence
Audacity
___ bladder
Vex
Temerity
Chutzpa
Irritate greatly
Presumptuousness
Unmitigated stuff
Chutzpah, in the extreme
Brazen boldness
Cheek
Some nerve!
Unmitigated ___
Rancor
Sass
Impudent boldness
Unmitigated nerve
Nerve, found in eight of the Across answers
Rancour, bitterness
Brazenness
Irritate big-time
Insolence
Really steam
Real nerve
Chutzpah in the extreme
Exasperate
Irk a lot
Presumption
Sioux chief
Irk big time
Impertinence
Irk big-time
"Unmitigated" nerve
"The unmitigated ___!"
Colossal nerve
Bitterness
Sometimes it's unmitigated
Chafe severely
Armada ship