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Answer: EDESSA
EDESSA is a crossword puzzle answer that we have spotted 20 times.
Early center of Christianity
Early capital of Macedonia
Ancient Macedonian city with noted tombs
Early center of Christianity in Mesopotamia
Ancient Turkish city now called Urfa
Capital of ancient Macedonia
City of ancient Mesopotamia
Ancient Macedonian capital
12th-century Crusader state
Greek regional capital
One of the Crusader states
Mesopotamian city
Macedonian city with Greek and Roman ruins
Historic Mesopotamian city
Ancient capital of Macedonia
Center of early Christianity in Mesopotamia
City in Central Macedonia
City WNW of Salonika
Early Macedonian capital
Mesopotamian metropolis