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Answer: BLOWIT
BLOWIT is a crossword puzzle answer that we have spotted 14 times.
Totally screw up
Mess up a good opportunity
Really mess things up, and what you might do to the last word of 24- or 51-Across, or 10-, 14-, or 34-Down
Mess up
Screw up
Blunder
Waste an opportunity
Fail big-time
Totally fail
Lose when you should have won, and a hint to the start of the answers to starred clues
Fail epically
Botch an opportunity
Botch the job
Spoil everything