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Answer: BESTIE
BESTIE is a crossword puzzle answer that we have spotted 15 times.
Closest bud
Closest friend, slangily
One's closest friend
Closest friend, informally
#1 bud
Number one pal
Lifelong pal
Favoritest friend
Super close friend
Closest pal
#1 pal
One whom you might tell *everything*
Principal pal
Closest confidant, informally
Ride-or-die pal