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Answer: ATWORST
ATWORST is a crossword puzzle answer that we have spotted 21 times.
If everything goes wrong
Pessimist's hypothetical
If all else fails
On one extreme
If everything fails
Least favorably
If everything else fails
Under the least favorable circumstances
Least optimally
If all goes wrong
Least desirably
Most unfavorably
Minimally
Under truly awful circumstances
If all goes awry
In the least favorable case
In the most dire circumstance
If everything fails miserably
"If all else fails ..."
"If the pessimists are right ..."
Under the most unfavorable circumstances