Answer: AMES
AMES is a crossword puzzle answer that we have spotted 225 times.
- Brothers' name of 40's-50's music
- City on the Skunk River
- Reformer Jessie
- Iowa State University site
- Spy in 1994 headlines
- City on the Skunk
- Cathy of "East of Eden"
- Home of the N.C.A.A.'s Cyclones
- Early American orator Fisher ___
- Home of Iowa State
- City half an hour north of Des Moines
- ___ Brothers of 40's-50's music
- Home of the Cyclones
- Cathy ___, "East of Eden" wife
- Site of Iowa State
- University town west of Cedar Rapids
- Skunk River city
- Spy Aldrich ___
- City southeast of Fort Dodge
- Spy Aldrich
- Singing family name
- Big Twelve Conference city
- Leon of "Mister Ed"
- Iowa State site
- "Rag Mop" brothers
- "Rag Mop" singers the ___ Brothers
- Iowa State city
- With 61-Down, a Big 12 campus city
- NASA's ___ Research Center
- Harry of the novel "The Man Who Cried I Am"
- Ed of "Daniel Boone"
- Colonial almanac compiler Nathaniel
- Traitorous Aldrich
- Ed who sang "My Cup Runneth Over"
- Infamous Aldrich
- Double agent Aldrich
- "Daniel Boone" actor
- Treasonous Aldrich
- Iowa State's home
- Singing brothers' name
- Actor Leon of "Life With Father"
- Iowa college town
- Iowa State's town
- Traitor Aldrich ___
- Rachel of "General Hospital"
- Bob ___, young man in Dreiser's "Sister Carrie"
- ___ Brothers, who sang "Rag Mop"
- ___ Building, first skyscraper in Boston
- Ed with the 1967 hit "My Cup Runneth Over"
- Actor Ed of "Daniel Boone"
- C.I.A. betrayer Aldrich
- University town near Des Moines
- Home of 14-Down
- Home of Iowa State University
- Where the Iowa Straw Poll is done
- C.I.A. betrayer arrested in 1994
- Iowa town
- Mingo portrayer Ed
- Home of the Iowa State Cyclones
- "Daniel Boone" star Ed
- Home of college football's Cyclones, with 53-Down
- "Daniel Boone" actor Ed
- Iowa State locale
- "Mister Ed" actor Leon
- Singing brothers
- Aldrich the spy
- "Aldrich ___: Traitor Within"
- Spydom's Aldrich
- Singer Ed
- 1990s spy Aldrich
- Billy Sunday's hometown
- Name of a NASA research center
- Iowa city
- Baritone Ed
- CIA turncoat Aldrich
- Corn Belt city on I-35
- Spy Aldrich arrested in 1994
- Billy Sunday's Iowa birthplace
- Iowa city on the Skunk River
- City near Des Moines
- Soviet spy Aldrich
- Iowa home of the Cyclones
- Iowa State home
- Home of the Big 12's Cyclones
- National Animal Disease Center's locale
- Big 12 Conference city
- "Rag Mop" brothers' last name
- Iowa State's setting
- Cyclones' city
- City in central Iowa
- With 57-Across, home of the Cyclones
- Iowa State University city
- Iowa straw poll city
- It's between Mason City and Des Moines on I-35
- Bankrupt discount store
- Iowa State's city
- Silicon Valley's NASA __ Research Center
- Academic Iowa city
- 1940s-'50s musical family name
- Singing brothers' surname
- ''My Cup Runneth Over'' singer
- With 114 Across, home of the Cyclones
- Corn Belt city
- Iowa State's place
- It's south of Mason City on I-35
- ''Rag Mop'' brothers
- Singing brothers of "Rag Mop"
- Brothers who sang ''Rag Mop''
- University city north of Des Moines
- City in Iowa
- ''Mister Ed'' actor Leon
- Leon in ''Mister Ed''
- ''My Cup Runneth Over'' singer Ed
- "Daniel Boone" co-star Ed
- City about 30 miles from Des Moines
- NASA ___ Research Center
- Traitor Aldrich
- "My Cup Runneth Over" singer
- City north of Des Moines
- Musical Brothers
- Mingo portrayer
- "Life With Father" co-star Leon
- Iowa State's locale
- Central Iowa city
- Ed who played Mingo on "Daniel Boone"
- "Daniel Boone" costar Ed
- ___ Brothers ("Rag Mop" singers)
- Columnist and graphic novelist Jonathan
- Surname of singing brothers Joe, Gene, Vic, and Ed
- Presidential straw poll city
- Home of a Big 12 school
- ___ Research Center (NASA lab in Silicon Valley)
- Midwest college town
- Isu location
- Brothers who sang "Rag Mop"
- Leon in "Mister Ed"
- Silicon Valley's NASA ___ Research Center
- "Undecided" Brothers
- CIA mole Aldrich
- Golfer Stephen
- Canadian golf pro, Stephen
- Ed or Leon
- Home to Iowa State University
- Souls to Serge
- Iowa university town
- Location of Iowa State University
- Iowa college city
- Iowa State setting
- 'My Cup Runneth Over' singer
- City of Iowa
- Iowa State's site
- 114 Across city
- "My Cup Runneth Over" singer Ed
- City in 22-Down
- ___ Straw Poll
- CIA spy Aldrich
- Subject of the 2012 book "Circle of Treason"
- "Rag Mop" singing brothers
- Home of college football's Cyclones
- Home city of the Big 12's Cyclones
- Midwestern college town
- Iowa city on I-35
- "Mingo" player Ed
- ___ Brothers; 1950's quartet
- With 27 Down, Big-12 school site
- Home to Iowa State
- Brothers who sang "You, You, You"
- Iowa State location
- It's north of Des Moines
- It's about 200 miles south of Minneapolis on I-35
- City of central Iowa
- Midwest university town
- College town north of Des Moines
- Iowa State University locale
- College town in Iowa
- Iowa State University location
- Hawkeye State city
- It's between Minneapolis and Kansas City on I-35
- Former Iowa Straw Poll city
- College city in 15 Across
- Singer/actor Ed
- "Peyton Place" denizen: 1957
- It's south of Minneapolis on I-35
- Actor Leon of "The Postman Always Rings Twice"
- College city on I-35
- American traitor
- Big 12 college town
- Cyclones play here
- Iowa Straw Poll city, once
- City in the Midwest's Story County
- '50s quartet "Brothers"
- Mingo's actor Ed
- Aldrich who was a spy for the K.G.B.
- It's north of Kansas City on I-35
- Nice souls in iowa?
- Iowa Department of Transportation city
- Stephen ____ ( Canadian PGA player )
- Home of the Iowa State Daily
- Barclay hope, on "the killing: michael ___
- Longtime Iowa straw poll city
- Where Carver taught in Iowa
- City in central 34-Across
- City that's home to Iowa State
- College town of George Washington Carver
- It's west of Cedar Rapids
- Iowa college city that isn't Iowa City
- Iowa campus city
- ___ Research Center
- City west of Cedar Rapids
- Iowa home of a Big 12 team
- Hawkeye State campus town
- College town in 11-Down
- College town west of Cedar Rapids
- Midwest center of agricultural research
- ___ Building, Boston's first skyscraper
- Iowa campus town
- Upper Midwest town with the world's tallest concrete gnome
- Hawkeye State college town
- Iowa city north of Des Moines
- Iowa State town
- Actor Leon ___
- Midwestern city that's an anagram of Mesa
- Hometown of the Iowa State Daily
- NASA ___: research center in Silicon Valley
- Campus site for 30,000 Iowa students